一、基本信息
1.姓名：彭爽
2.性别：男
3.出生年月：1983年12月
4.籍贯：湖南岳阳
5.学位： 博士 （国家留学基金委公派博士）
6.职称： 副教授
7.专业： 运动人体科学
8.所在部门：运动与健康学院
二、专业及研究方向
1. 主要学术经历：
（1）2018-2022，暨南大学，基础医学与公共卫生学院，病理生理学系，副教授
（2）2017-2018，英国卡迪夫大学，博士后
（3）2011-2017，英国卡迪夫大学，博士（Ph.D）/硕士（MPhil)
（4）2010-2016，暨南大学，博士（病理学与病理生理学）/硕士（生理学）
2.研究方向：运动与健康促进; 消化系统疾病的运动康复机制；细胞信号转导
三、主要研究成果（近五年）
（一）著作与教材
1.《简明医学机能学实验指导》，北京大学出版社，2023
2.《病理生理学实验指导及病例分析》，暨南大学出版社，2022
3.《Drug Delivery to Tumor-Recent Strategies and Techniques》，Springer Nature，2023
（二）主持科研项目
1. 主持广东省自然科学基金面上项目（2021A1515010740）, eATP激活嘌呤能信号通路在调控胰腺微环境炎性反应中的机制研究, 10万元, 2021-2023。
2. 主持广州市基础研究计划基础与应用基础研究项目（202102080176），钙信号调控胰腺星状细胞活化在急性胰腺炎发病机制中的作用研究, 5万元, 2021-2023。
3. 主持广州体育学院青年博士资助类科研项目, 20万元, 2023-2025。
4. 主持科技部国家外国专家项目高端外国专家引进计划（G2021199018L），细胞信号转导与胰腺疾病前沿研究, 20万元, 2021-2022。
5. 主持广东省科学技术厅 “海外名师”项目，胰腺疾病的前沿研究与临床转化，5万元，2021-2023。
（三）公开发表与入选各类论文报告会的论文
1. Lei Zuo, Xia Chen, Mingliang Liu, Li Chen, Wenbin Xu, Haiyan Chen, Shan Dong, Yuan Wei*, Liangming Li*, Shuang Peng*, Guang Hao*. Road Traffic Noise, Obesity, and the Risk of Incident Type 2 Diabetes: A Cohort Study in UK Biobank. Int J Public Health. 2022;67:1605256. (IF:5.1，共同通讯作者)
2. Meisheng Yu#, Yuan Wei#, Pengyuan Wang, Zhiqin Deng, Jianwen Mao, Linyan Zhu, Lixin Chen*, Shuang Peng*, Liwei Wang*. Excess iodide-induced reactive oxygen species elicit iodide efflux via β-tubulin-associated ClC-3 in thyrocytes. Biochem J. 2022;479(5):629-640. (IF:3.857，共同通讯作者)
3. Shuang Peng. Transient Receptor Potential Ankyrin 1 Channels in Inflammation and Cancer: Accelerators or Brakes? Function (Oxf). 2022;3(5):zqac049. (第一兼通讯作者)
4. Ole H Petersen*, Julia V Gerasimenko, Oleg V Gerasimenko, Oleksiy Gryshchenko, Shuang Peng*. The Roles of Ca2+ and ATP in the Physiology and Pathology of the Exocrine Pancreas, Physiol Rev. 2021;101(4):1691-1744. (IF:37.312，共同通讯作者)
5. Yuan Wei#, Chaoqun Liu#, Fangfang Lai#, Shan Dong#, Haiyan Chen, Li Chen, Liping Shi, Fengfeng Zhu, Chuangbiao Zhang, Xiuxiu Lv*, Shuang Peng*, Guang Hao*. Associations between serum total bilirubin, obesity and type 2 diabetes. Diabetol Metab Syndr. 2021;13(1):143. (IF:3.32，共同通讯作者)
6. Meisheng Yu#, Yuan Wei#, Yanfang Zheng, Lili Yang, Long Meng, Jiawei Lin, Peisheng Xu, Sanaa Ahmed Nagi Abdu Mahdy, Linyan Zhu, Shuang Peng*, Lixin Chen*, Liwei Wang*. 17β-Estradiol activates Cl- channels via the estrogen receptor α pathway in human thyroid cells. Channels (Austin). 2021;15(1):516-527. (IF:2.581，共同通讯作者)
7. Chen Qu#, Lu He#, Nan Yao, Jinying Li, Yuchuan Jiang, Binkui Li, Shuang Peng, Kunpeng Hu, Dong Chen, Guo Chen, Wei Huang, Mingrong Cao, Jun Fan, Yunfei Yuan, Wencai Ye*, Jian Hong*. Myofibroblast-Specific Msi2 Knockout Inhibits HCC Progression in a Mouse Model. Hepatology. 2021;74(1):458-473. (IF:17.425)
8. Yu Yan#, Guang Wang#, Xin Luo, Ping Zhang, Shuang Peng, Xin Cheng, Mengwei Wang, Xuesong Yang. Endoplasmic reticulum stress-related calcium imbalance plays an important role on Zinc oxide nanoparticles-induced failure of neural tube closure during embryogenesis. Environ Int. 2021;152:106495.(IF:9.621)
9. Li Chen#, Haiyan Chen#, Shan Dong#, Wei Huang#, Li Chen, Yuan Wei, Liping Shi, Jinying Li, Fengfeng Zhu, Zhu Zhu, Yiyang Wang, Xiuxiu Lv, Xiaohui Yu, Hongmei Li, Wei Wei, Keke Zhang, Lihong Zhu, Chen Qu, Jian Hong, Chaofeng Hu, Jun Dong, Renbin Qi, Daxiang Lu, Huadong Wang*, Shuang Peng*, Guang Hao*. The Effects of Chloroquine and Hydroxychloroquine on ACE2-Related Coronavirus Pathology and the Cardiovascular System: An Evidence-Based Review. Function (Oxf). 2020;1(2):zqaa012. (共同通讯作者)
10. Zhen Shu#, Zhen Li#, Huanhuan Huang#, Yan Chen, Jun Fan, Li Yu, Zhihui Wu, Ling Tian, Qi Qi, Shuang Peng, Changyong Wei, Zhongqiu Xie, Xiaobo Li, Qi Feng, Hao Sheng, Guangqiang Li, Dongping Wei, Changliang Shan, Guo Chen. Cell-cycle-dependent phosphorylation of RRM1 ensures efficient DNA replication and regulates cancer vulnerability to ATR inhibition. Oncogene. 2020;39(35):5721-5733. (IF:9.867)
11. Shuang Peng, Ole H. Petersen*. One or Two Ca2+ Stores in the Neuronal Endoplasmic Reticulum? Trends Neurosci. 2019;42(11):755-757. (IF:13.837，第一作者)
12. Yanfang Zheng#, Zhanru Chen#, Zhuoyu Gu, Xiaoya Yang, Meisheng Yu, Chan Zhao, Jiawei Lin, Peisheng Xu, Linyan Zhu, Tim J C Jacob, Shuang Peng*, Lixin Chen*, Liwei Wang*. Starvation-induced autophagy is up-regulated via ROS-mediated ClC-3 chloride channel activation in the nasopharyngeal carcinoma cell line CNE-2Z. Biochem J. 2019;476(9):1323-1333. (IF:4.097，共同通讯作者)
13. Shuang Peng#, Julia V Gerasimenko#, Tetyana M Tsugorka, Oleksiy Gryshchenko, Sujith Samarasinghe, Ole H Petersen, Oleg V Gerasimenko. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 2018;128(9):3769-3778.(IF:13.251，第一作者)
14. Oleksiy Gryshchenko#, Julia V Gerasimenko#, Shuang Peng, Oleg V Gerasimenko, Ole H Petersen. Calcium signalling in the acinar environment of the exocrine pancreas: physiology and pathophysiology. J Physiol. 2018;596(14):2663-2678.(IF:4.739)
15. J.V.Gerasimenko*, S.Peng, T.Tsugorka, O.V.Gerasimenko*. Ca2+ signalling underlying pancreatitis. Cell Calcium.2018;70:95-101.(IF:3.707)
16. Zhiqin Deng#, Shuang Peng#, Yanfang Zheng, Xiaoya Yang, Haifeng Zhang, Qiuchan Tan, Xiechou Liang, Hong Gao, Yuan Li, Yanqing Huang, Linyan Zhu, Tim J C Jacob, Lixin Chen*, Liwei Wang*. Estradiol activates chloride channels via estrogen receptor-α in the cell membranes of osteoblasts. Am J Physiol Cell Physiol. 2017;313(2):C162-C172.(IF: 3.602，并列第一作者)
17. Shan-Wen Liu#, Yuan Li#, Li-Li Zou, Yu-Tao Guan, Shuang Peng, Li-Xin Zheng, Shun-Mei Deng, Lin-Yan Zhu, Li-Wei Wang*, Li-Xin Chen*. Chloride channels are involved in sperm motility and are downregulated in spermatozoa from patients with asthenozoospermia. Asian J Androl. 2017;19(4):418-424.(IF:2.644)
18. Shuang Peng, Julia V Gerasimenko, Tatiana Tsugorka, Oleksiy Gryshchenko, Sujith Samarasinghe, Ole H Petersen*, Oleg V Gerasimenko*. Calcium and ATP control of cellular pathology: Asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci. 2016;371(1700):20150423.(IF:7.055，第一作者)
19. Haifeng Zhang#, Zhiqin Deng#, Lili Yang#, Hai Luo, Shanwen Liu, Yuan Li, Yan Wei, Shuang Peng, Linyan Zhu, Liwei Wang*, Lixin Chen*. The AQP-3 water channel is a pivotal modulator of glycerol-induced chloride channel activation in nasopharyngeal carcinoma cells. Int J Biochem Cell Biol. 2016;72:89-99.(IF:4.046)
20. Julia Gerasimenko, Shuang Peng, Oleg Gerasimenko. Role of acidic stores in secretory epithelia. Cell Calcium. 2014;55(6):346-54.(IF:4.21)
21. Julia V Gerasimenko#, Oleksiy Gryshchenko#, Pawel E Ferdek#, Eloise Stapleton, Tania O G Hébert, Solomiia Bychkova, Shuang Peng, Malcolm Begg, Oleg V Gerasimenko*, Ole H Petersen*. Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy. Proc Natl Acad Sci U S A. 2013;110(32):13186-91.(IF:9.809)
22. Pawel E Ferdek, Julia V Gerasimenko, Shuang Peng, Alexei V Tepikin, Ole H Petersen, Oleg V Gerasimenko. A novel role for Bcl-2 in regulation of cellular calcium extrusion. Curr Biol. 2012;22(13):1241-6.(IF:10.025)
会议报告：
1. 第39届国际生理科学联合会大会(IUPS2022)，2022-5，北京，专题报告：Tuning of calcium signaling and oxidative stress in pancreatic inflammatory control。
2. 中国病理生理学会消化专业委员会六届三次会议暨2021年度学术年会，2021-12，山西太原，专题报告：钙信号与急性胰腺炎。
3. 第十二届全国抗炎免疫药理学学术交流会，2019-12，广东广州，专题报告：钙信号与ATP在急性胰腺炎发病机制中的作用。
4. 欧洲科学院转化医学前沿国际会议，2019-9，匈牙利布达佩斯，专题报告：Translational Medicine for achieving Healthy China 2030。
5. 欧洲科学院生理学与病理生理学大会，2018-3，英国卡迪夫，专题报告：In vivo studies of Asparaginase induced pancreatic acinar pathophysiology。
（四）获奖成果
1. 获得广东省教育厅第九届师德主题微视频一等奖（团队参与成员）
2. 获得2016年欧洲科学院Burgen Scholar
四、社会兼职
中国生理学会消化与营养专业委员会委员，中国药理学会抗炎免疫药理专委会青年委员，英国卡迪夫大学Honorary Research Fellow，国际学术期刊《Function》、《Frontiers in Physiology》与中国科技期刊卓越行动计划梯队期刊《中国病理生理杂志》编委，暨南大学欧美同学会理事。